URB597

URB597

Author: ApexBio

spu:

A4372

CAS:

546141-08-6

purity:

0.9958

shortsummary:

FAAH inhibitor,potent and selective

210344-95-9 site

Synonyms:

FAAH Inhibitor II, URB-597, URB 597, KDS-4103

58880-19-6 APExBIO

Formula:

C20H22N2O3

M.Wt:

338.4

Chemical Name:

[3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate

SMILES:

C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N

Solubility:

insoluble in H2O; ≥16.9 mg/mL in DMSO; ≥4.55 mg/mL in EtOH with gentle warming and ultrasonic

Storage:

Store at -20°C

DeliveryTime:

In stock

Tianeptine sodium Description

ShippingType:

Blue ice

description:

URB597, also known as KDS-4103, is a potent and selective inhibitor of fatty-acid amide hydrolase (FAAH), an enzyme catalyzing the intracellular hydrolysis of the endocannabinoid anandamide, with values of 50% inhibition concentration IC₅₀ of 5 nM and 3 nM in rat brain membranes and human liver microsomes respectively. Study results have shown that, through intraperitoneal (i.p.) administration, URB597 potently inhibits FAAH in rat brain with a median inhibitory dose ID₅₀ of 0.15 mh/kg. However, URB597 fails to show significant inhibition against a few other cannabinoid-related targets (such as cannabinoid receptors and anandamide transport) as well as a broad range of receptors, ion channels, transporters and enymes.

related websites:

APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 1317 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.